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Adenovirus is a double-stranded DNA virus with an envelope-free, icosahedral structure of 70-100 nm in diameter. Adenoviruses can infect all vertebrates, including mammals, birds, reptiles, and fish. Most adenoviruses are species-specific, but some adenoviruses can infect multiple hosts. Adenovirus infections cause different symptoms in different animals, such as affecting the respiratory and gastrointestinal systems of animals, seizures, hemorrhagic disease, coma and death. Adenovirus is transmitted mainly through direct contact with infected animals or indirect contact with their nasal secretions, urine and feces. In addition, adenovirus can be transmitted through the air, contaminated water, and contaminated equipment.
Figure 1. (Left) Cryo-electron reconstruction of a particle of a human adenovirus 2 particle. (Center) Stylized section of a mastadenovirus particle showing capsid (II, III, IIIa, IV, VI, VIII, IX) and core (V, VII, X and TP (terminal protein)) proteins. (Right) Fowl adenovirus 9 particle negatively stained with uranyl acetate, showing the characteristic double fibers of fowl adenoviruses (MacLachlan, N. J., et al. 2017).
Adenovirus Virus Isolation Kit Development
Adenovirus was originally isolated from human glands by Wallace Rowe and colleagues and was named for its isolation from the glandular tissue of the host. The widespread spread of adenovirus in animals has caused significant economic losses to livestock and poultry breeders. Therefore, it is important to develop kits for effective detection of animal adenovirus. Virus isolation techniques are often considered the "gold standard" for adenovirus diagnosis, and the final result of adenovirus isolation by tissue culture usually takes several days.
BioVenic is a supplier of biological reagents and kits, and has been working on the development of animal virus diagnostic reagents for many years. We have a team of professionals with extensive experience in cell culture, virus isolation and kit development. We can develop a range of adenovirus isolation kits to diagnose adenovirus infection. If you have any needs, please feel free to contact us. We will provide you with high-quality products and services.
The Adenovirus Isolation Kits We Can Develop
Bovine adenovirus isolation kit
Equine adenovirus isolation kit
Goat adenovirus isolation kit
Cat adenovirus isolation kit
Duck adenovirus isolation kit
Canine adenovirus isolation kit
Porcine adenovirus isolation kit
Sheep adenovirus isolation kit
Chicken adenovirus isolation kit
Goose adenovirus isolation kit
Workflow of Adenovirus Isolation Kit Development
| Workflow | Details |
|---|---|
| Sample collection | Samples are collected from infected animals. |
| Cell culture | Adenovirus samples were inoculated onto the culture medium for propagation. |
| DNA isolation and purification | Isolation and purification of adenovirus DNA from cell culture fluid. |
| Structural analysis of adenovirus | The isolated adenovirus nucleic acid and protein coat were analyzed. |
| Adenovirus isolation kit development | Development of kit to isolate adenovirus. |
| Adenovirus isolation kit delivery | We will provide you with customized adenovirus isolation kits and complete product quality inspection reports. |
Delivery
- A series of adenovirus isolation kits
- Product quality inspection report (COA)
- Other experimental data you need
Our Advantages
- High sensitivity and specificity
- Isolation of viruses from multiple samples
- Reasonable price and short turnaround time
Reference
- MacLachlan, N. J., and E. J. Dubovi. "Chapter 10-Adenovirus. Fenner's Veterinary Virology." (2017).
