Viruses are ubiquitous microorganisms that exist wherever there is life. Viruses can infect all living organisms with a cellular structure. When animals are infected with viruses, they can cause various animal diseases, even leading to zoonotic diseases and global outbreaks, such as SARS-CoV-2. The spread of viruses is inextricably linked to the replication of their genomes. The viral genome consists of a nucleic acid molecule (DNA or RNA). Depending on the composition of the genetic material, they can be classified as single-stranded/double-stranded DNA viruses and single-stranded/double-stranded RNA viruses. The genomes of viruses are small, e.g., the RNA genome of SARS-CoV-2 is about 30 kb.
Figure 1. A complete protocol for whole-genome sequencing of virus from clinical samples (Maurier, Florence, et al., 2019).
The genome sequence of an animal virus is the sequence of the bases that make up the genome of the virus. Genome sequencing of animal viruses is an effective tool for understanding virus pathogenicity and transmission routes and monitoring virus epidemiology. In virus research and related production, the traditional Sanger sequencing method can only amplify and sequence specific sequences of viruses with known sequences, while high-throughput sequencing technology can sequence the whole genome of viruses and use biological information analysis to obtain the whole genome sequence of viruses, parse coding information, and obtain corresponding variation information. Unlike DNA virus sequencing, RNA virus sequencing requires reverse transcription to convert RNA sequences into DNA sequences before sequencing.
BioVenic is a supplier of animal virus sequencing kits and has been working on the development of animal virus sequencing related products for many years. We have a professional team with rich experience in the field of animal genome sequencing and molecular diagnosis, and we also have a professional kit development platform to provide you with a series of customized animal virus sequencing kits and related products according to your needs. If you have any needs, please feel free to contact us. We will provide you with high-quality products and services.
Library prep kit | DNA/ RNA extraction kit |
PCR product purification kits | Sequencing purification kit |
Avian rotavirus genome sequencing kit development | Bluetongue virus genome sequencing kit development |
Influenza virus genome sequencing kit development | Canine distemper virus genome sequencing kit development |
Canine parvovirus genome sequencing kit development | Feline panleukopenia virus genome sequencing kit development |
Reference