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Coronaviruses belong to the order Nesteviridae, the family Coronaviridae, and the genus Coronaviridae. They are a class of RNA viruses with an envelope and a linear single-stranded positive-stranded genome. The coronavirus genome has a methylated cap-like structure at the 5' end and a poly(A) tail at the 3' end. The total length of the genome is about 27-32 kb, and it is the virus with the largest genome among the known RNA viruses. According to the phylogenetic tree, coronaviruses can be divided into four genera: α, β, γ, δ, of which β coronaviruses can be divided into four independent subgroups A, B, C and D. Animal coronaviruses include mammalian coronaviruses and avian coronaviruses. Mammalian coronaviruses are mainly alpha and beta coronaviruses, which can infect a variety of animals including bats, pigs, dogs, cats, mice, cattle, horses, etc. Avian coronaviruses are mainly derived from gamma and delta coronaviruses, which can infect a variety of birds such as chickens, turkeys, sparrows, ducks, geese, pigeons, etc.
Figure 1. COVID-19 animal models and susceptible animals. (A) Mouse models: hACE2 transgenic mouse, hACE2-transdued mouse, and mouse-adapted SARS-CoV-2. (B) Golden hamster model. (C) Ferret model. (D) No human primates: Rhesus macaque model and Cynomolgus macaque model. (E) Pig model. (F) Other susceptible animals (Wang, Shen, et al. 2021).
Coronavirus Isolation Kit Development
Coronaviruses can not only cause respiratory, digestive and nervous system diseases in animals, but also cause zoonotic pandemic diseases, such as SARS, MERS, COVID-19, etc., which has a serious impact on the health of people and animals around the world, and has caused huge economic losses. Therefore, the development of kits for isolation and identification of coronaviruses is very important for the control and treatment of diseases caused by coronaviruses. Virus isolation technology is a commonly used method for isolating coronaviruses in laboratories, and researchers have developed a series of coronavirus isolation reagents.
BioVenic is a leading supplier of diagnostic reagents for animal diseases, serving veterinarians, animal disease researchers and animal breeders. With our advanced technology platform and professional technicians, we can provide you with a series of coronavirus isolation kits for the study of coronavirus traits, pathogenicity, susceptible organs, pathogenesis, and drug susceptibility to control the widespread of animal diseases. If you have any needs, please feel free to contact us. We will provide you with high-quality products and services.
The Coronavirus Isolation Kits We Can Develop
Bovine coronavirus isolation kit
Equine coronavirus isolation kit
Goat coronavirus isolation kit
Feline coronavirus isolation kit
Turkey coronavirus isolation kit
Duck coronavirus isolation kit
Bat coronavirus isolation kit
Canine coronavirus isolation kit
Porcine coronavirus isolation kit
Sheep coronavirus isolation kit
Chicken coronavirus isolation kit
Pigeons coronavirus isolation kit
Goose coronavirus isolation kit
Other coronavirus isolation kit
Workflow of Coronavirus Isolation Kit Development
| Workflow | Details |
|---|---|
| Sample collection | Samples are collected from infected animals. |
| Cell culture | Samples were inoculated onto the culture medium for propagation. |
| RNA isolation and purification | Isolation and purification of coronavirus RNA from cell culture fluid. |
| Structural analysis of coronavirus | The isolated coronavirus acid and protein coat were analyzed. |
| Coronavirus isolation kit development | Development of kit to isolate coronavirus. |
| Coronavirus isolation kit delivery | We will provide you with customized coronavirus isolation kits and complete product quality inspection reports. |
Delivery
- A series of coronavirus isolation kits
- Product quality inspection report (COA)
- Other experimental data you need
Our Advantages
- Reliable results
- Advanced equipment and professional technicians
- Reasonable price and short turnaround time
Reference
- Wang, Shen, et al. "COVID-19 Animal Models and Vaccines: Current Landscape and Future Prospects." Vaccines 9.10 (2021): 1082.
