Sheep Antibodies

Sheep are a domesticated ruminant mammal, usually kept as livestock. Sheep were originally raised for wool, meat and milk. In recent years, with the continuous development of the field of biomedicine, sheep have been used as animal models for the study of diseases, such as Huntington's disease and Barton's disease. Sheep farming is also developing rapidly with the increasing demand for sheep. The control of sheep diseases is very important to the sheep breeding industry, because sheep diseases will affect the health status of sheep and the quality of sheep products, and even lead to the death of sheep, causing huge economic losses to the breeding industry. As a kind of disease diagnosis reagent, sheep antibodies are widely used in the study of sheep immune response and plays an important role in disease control.

Sheep Antibodies

Sheep have 5 immunoglobulin isotypes (i.e., IgM, IgG, IgA, IgD and IgE). The IgG class is further subdivided into 3 subtypes (IgG1, IgG2, and IgG3). In sheep, as in other species, the heavy chain is bound to 2 light chains (λ and kappa), and IgG-lambda accounts for 95% of IgG in sheep. The production of antigen-specific antibodies is the main defense mechanism of the humoral immune response. After the sheep antigen enters the antibody-producing host, cellular products (such as cytokines) and immune cells (T helper cells, B cells, and antigen-presenting cells) will synergistically produce antigen-specific sheep antibodies. B cells and plasma cells produce sheep antigen-specific antibodies and release them into the systemic circulation several days after the host animal is exposed to highly purified sheep antigens. Mouse, rabbits and donkeys are common host animals for the production of sheep antibodies.

BioVenic is a company developing veterinary antibodies for the diagnosis of various animal diseases. We have a state-of-the-art antibody development platform and our R&D staff have extensive working experience in genomics, proteomics, signaling pathways and immunology. Sheep is a host for antibody production, and our researchers have developed monoclonal antibodies against sheep CD markers, sheep cytokines, and sheep immunoglobulins, which are available to you in a variety of formats. All of our antibodies undergo strict quality control and can be used with a variety of conjugates to study the sheep's immune response and improve their health of sheep. These products are suitable for a variety of detection methods including Western blotting, ELISA, immunofluorescence, immunoprecipitation, flow cytometry and immunohistochemistry. If you have any needs, please feel free to contact us. We will choose the right products for you according to your needs.