Immunoglobulin (Ig) serotype is a manifestation of immunoglobulin heterogeneity, and its function and structure are based on the existence of a variety of different antigenic epitopes in the immunoglobulin polypeptide chain molecule, thereby showing different immunogenicity and stimulating the body to produce corresponding serotypes. of anti-Ig antibodies. Ig serotype is the molecular basis for distinguishing immunoglobulin classes and subclasses, types and subtypes, and plays an important role in the immune regulation of the body.
Figure 1. The structure of immunoglobulin molecule. L-light chains; H-heavy chains; V-variable area; C-constant area.
The following are some common bovine immunoglobulins. Researchers have studied a series of bovine immunoglobulin antibodies against these bovine immunoglobulins, which can be used to detect immunoglobulins in bovine blood and plasma and thus assess the health status of cattle to provide a basis for diagnosis and control of bovine diseases.
Type | Description |
Bovine immunoglobulin A | IgA is an immunoglobulin secreted on the surface of the gut, genitourinary tract, and respiratory tract that protects against viruses and bacteria from adhering to epithelial tissues. Found in bovine saliva, colostrum, milk, tear duct fluid, urine and nasal fluid. |
Bovine immunoglobulin M | IgM expressed by bovine B-cells. |
Bovine immunoglobulin E | IgE is an immunoglobulin mainly produced by plasma cells and is present in very low concentrations in normal serum. |
Bovine immunoglobulin G | Bovine IgG includes both IgG1 and IgG2. Normal serum IgG1 levels in cattle are relatively constant at around 50%, but IgG2 levels vary widely between strains and races. |
Rapid diagnosis of bovine diseases is essential to reduce bovine mortality and economic losses to the livestock industry. BioVenic, a veterinary antibody supplier, has been developing antibody reagents for many years. Our technical staff has extensive experience working in the field of veterinary diagnostics and antibody development. We are also equipped with advanced instrumentation to ensure the accuracy of our assays. So we can offer you a range of antibodies against bovine immunoglobulins to diagnosis of bovine diseases and assessment of the overall health of the bovine. If you have any needs, please feel free to contact us.