Dogs are good companions of humans and become part of the human family as companion pets. Due to the influence of various factors such as living environment, food type, exercise rest, breed and age, dogs may be infected with some pathogens at different growth stages and cause related diseases. Common diseases in dogs can be divided into infectious, non-infectious and non-specific diseases. Rabies, canine parvovirus, and canine distemper are the most common canine infectious diseases, and they are also diseases that are more dangerous and lead to higher mortality in dogs, especially rabies, which can be transmitted between humans, dogs, cats, and wolves and is very dangerous. The most common canine nonspecific diseases include gastroenteritis, ear leakage, dermatitis, and alopecia. And cancer, abortion, fractures, lacerations, diabetes and vitamin deficiencies are the most common of the canine non-infectious diseases. Canine diseases not only affect human health, but also bring economic losses to human beings. Therefore, it is very important to understand the epidemiology of these canine diseases and effectively prevent and control them to reduce human economic losses.
Figure 1. Pathogenesis of rabies virus. 1) Virus enters muscle tissue of host through bite wound, then 2) enters the peripheral nervous system (PNS) via neuromuscular junction, and then 3) travels from PNS to spinal cord and brain. 4) Virus enters brain and undergoes extensive replication leading to neuronal dysfunction (slide shows virus in Purkinje cells of cerebellum 40x magnification). 5a) The virus replicates in salivary glands and is excreted in saliva, 5b) enters peripheral nerves of skin and Purkinje cells, and 5c) spreads from the brain to infect many tissues and organs in the host (Fooks, et al., 2014).
Canine Disease Antibodies / Pathogens
Pet dogs are susceptible to a variety of diseases whose pathogens include fungi, bacteria, viruses, parasites, and protozoa. Among them, infectious pathogens can be transmitted among dogs, cats, other animals and humans, which can cause public health problems and socioeconomic losses. However, the diagnosis of canine diseases is complex because the clinical signs of canine diseases are nonspecific. To rapidly and specifically diagnose canine diseases, BioVenic has developed a series of antigens and antibodies to detect labeled proteins from different samples. Currently, these products are used in a variety of diagnostic methods for canine diseases, such as enzyme-linked immunosorbent assay (ELISA), immunoturbidimetry, colloidal gold immunochromatographic assay, chemiluminescence immunoassay (CLIA), lateral flow Immunoassay (LFIA) and POCT.
BioVenic is a supplier of biological reagents and kits, and has been developing diagnostic reagents for animal pathogens for many years. Our goal is to be a great company that improves the health and well-being of pets and livestock. With a professional antibody/antigen development technology platform and research team who have extensive experience in veterinary diagnostics and kit development, we can provide you with a variety of antigens / antibodies to effectively detect canine diseases at an early stage. If you have any needs, please feel free to contact us. We will provide you with high-quality products according to your needs.
Reference
- Fooks, Anthony R., et al. "Current status of rabies and prospects for elimination." The Lancet 384.9951 (2014): 1389-1399.
