Ruminant Abortion Virus VN Kit Development

Many of the toxins can cause abortion in cows and also cause problems in ewes. A significant non-contagious, arthropod-borne infectious viral illness affecting ruminants is known as the bluetongue virus. Bluetongue virus has recently been found associated with abortion and sudden infant deaths in mares. It is also a cause of abortion, fetal mummification, stillbirth, and congenital brain malformation in lambs. Border disease is a viral disease of sheep and goats that occurs worldwide and is an important cause of embryonic and fetal deaths, weak lambs, and congenital abnormalities. It is caused by a pestivirus closely related to the bovine viral diarrhea (BVD) virus and classical swine fever (hog cholera) virus. Cache Valley virus is also a cause of infertility, abortions, stillbirths, and multiple congenital abnormalities in sheep. The virus is endemic in most parts of the USA, Canada, and Mexico. Abortion in ruminants is not always easily diagnosed, so the development of novel diagnostic methods is crucial for the control of ruminant abortion caused by viruses.

Figure 1. Structure of orthobunyavirus (Elliott, et al., 2014).

Ruminant Abortion Virus VN Kit Development

Reproductive failure due to abortion disease is causing a significant revenue drain in many ruminant livestock production systems every year. Successful abortion diagnosis in ruminants involves input from the producer, practitioner, and diagnostician. Numerous improvements in test development have given the diagnostician powerful tools for etiologic diagnosis. A popular technique for finding subgroup-specific antibodies against ruminant abortion illnesses is the viral neutralization (VN) test. Antibodies can neutralize viruses by blocking attachment to the host cell, preventing the penetration of the host cell membrane, or interfering with the uncoating of the virus within the cell. In the VN test, the presence or absence of viral growth can be observed. This method can be used to find poisons, diagnose diseases, and identify antibodies. VN test is widely used due to its excellent sensitivity and specificity. The neutralizing antibody can be used to differentiate viruses at the strain level.

BioVenic is a supplier of biological reagents and kits, and has been developing diagnostic reagents for animal viruses for many years. Our goal is to be a great company that improves the health and well-being of pets and livestock. We have a professional team with extensive experience in veterinary diagnostics and reagent development, and we can provide you with a series of customized virus neutralization kits for the detection of ruminant abortion virus based on your needs. If you have any queries, please feel free to contact us. We will provide you with high-quality products and services.

Ruminant Abortion Virus VN Kits We Can Provide

Workflow of Ruminant Abortion Virus VN Kit Development

Delivery

• Report on product inspection quality
• Other experimental data you need
• A series of VN kits for ruminant abortion viruses

Our Advantages

• High specificity and high sensitivity
• High throughput assessment
• Viral pathogens or their toxins can be detected
• The level of serological cross-reactivity can be detected