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Caliciviruses are single-stranded positive-sense RNA viruses with non-enveloped viral particles approximately 35-39 nm in diameter. Calicivirus genomes are approximately 7-8 kb in length, and their capsids include 180 individual capsid protein molecules. The international committee on taxonomy of viruses (ICTV) divides the Caliciviridae into five genera, Lagovirus, Vesivirus, Sapovirus, Nebovirus and Norovirus. Caliciviruses can infect a variety of animals and cause diseases, such as vesicular rash, stomatitis, respiratory diseases, gastroenteritis, conjunctivitis or bleeding diseases, which seriously threaten animal health.
Figure 1. Raw images of labeled FCV virions were sorted into six classes according to the extent of the conformational change they had undergone, and three-dimensional reconstructions were calculated for every class for which there were sufficient data. Stereo pairs are shown for classes 1 to 5 (A to E, respectively) (Bhella, David, et al. 2011).
Calicivirus Isolation Kit Development
Calicivirus poses a threat to the health of animals such as rabbits, cows, pigs, cats and dogs, as well as economic losses to animal breeders. In addition, caliciviruses can also cause outbreaks of foodborne illnesses that affect public health. In order to accurately diagnose calicivirus-related diseases, virus isolation techniques are widely used for the study of viral receptors, entry routes, etc. BioVenic is a company specializing in animal virology research, dedicated to safeguarding the health of poultry, livestock, companion animals and wildlife. We can provide you with a variety of calicivirus isolation kits for the diagnosis of animal diseases. If you have any needs, please feel free to contact us.
The Calicivirus Isolation Kits We Can Develop
Rabbit hemorrhagic disease virus isolation kit
Feline calicivirus isolation kit
Bovine norovirus isolation kit
Canine norovirus isolation kit
Swine vesicular exanthem virus isolation kit
Bovine norovirus isolation kit
Porcine sapovirus isolation kit
Other calicivirus isolation kit
Workflow of Calicivirus Isolation Kit Development
| Workflow | Details |
|---|---|
| Sample collection | Samples are collected from infected animals. |
| Cell culture | Samples were inoculated onto the culture medium for propagation. |
| RNA isolation and purification | Isolation and purification of calicivirus RNA from cell culture fluid. |
| Structural analysis of calicivirus | The isolated calicivirus acid and protein coat were analyzed. |
| Calicivirus isolation kit development | Development of kit to isolate calicivirus. |
| Calicivirus isolation kit delivery | We will provide you with customized calicivirus isolation kits and complete product quality inspection reports. |
Delivery
- A series of calicivirus isolation kits
- Product quality inspection report (COA)
- Other experimental data you need
Our Advantages
- Accurate and reliable results
- Advanced equipment and professional technicians
- Reasonable price and short turnaround time
References
- Bhella, David, and Ian G. Goodfellow. "The cryo-electron microscopy structure of feline calicivirus bound to junctional adhesion molecule A at 9-angstrom resolution reveals receptor-induced flexibility and two distinct conformational changes in the capsid protein VP1." Journal of Virology 85.21 (2011): 11381-11390.
- Guo, Zijing, et al. "First detection of Nebovirus and Norovirus from cattle in China." Archives of Virology 163.2 (2018): 475-478.
