Virus Neutralization (VN) Kit Development

In recent years, animal virus infection has caused a variety of animal diseases, such as rabies, avian influenza, feline leukemia, feline distemper, etc., also has caused serious impacts on the public health of society. Virus neutralization is the gold standard test for virus serological identification. The test is based on the fact that specific antiviral antibodies (neutralizing antibodies) bind to the virus, causing the virus to lose its ability to adsorb and penetrate host cells, thereby preventing the replication of the virus within the host cell and the process of viral infection of the organism. VN antibodies are probably the most widely studied type of antibody in virology because they are persistent and directly related to immunity in vivo.

Figure 1. Interaction of SARS-CoV-2 with its receptors and neutralization mechanisms (Morales-Núñez, et al., 2021).

VN Kit Development

Virus infection is one of the important causes of zoonotic diseases. According to reports, the vast majority of emerging infectious diseases in the world are related to animals, including many previously unknown new viruses, such as Nipah virus and coronavirus. The rapid spread of these viruses not only affects livestock production and reduces food supply, but also affects the public health environment and causes huge economic losses. Therefore, it is crucial to develop a method to specifically detect viral infection in animals. Virus neutralization is a serological assay that is widely used in the detection of animal viruses. This method has high sensitivity, but its standardization is difficult and its sensitivity may vary in different laboratories. So, researchers need to choose the appropriate method according to their needs.

BioVenic is a supplier of biological reagents and kits, and has been developing diagnostic reagents for animal viruses for many years. Our goal is to be a great company that improves the health and well-being of animal. We have a professional team with extensive experience in veterinary diagnostics and kit development, and we can customize a range of VN kits for animal pathogen detection based on your needs. If you have any needs, please feel free to contact us, we can provide you with high-quality products and services.

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