Antigens (Ag) are all substances that can induce an immune response in the body. That is, they can be specifically recognized and bound by antigen receptors (TCR/BCR) on the surface of T/B lymphocytes and activate T/B cells to proliferate and differentiate to produce immune response products (sensitized lymphocytes or antibodies). They can specifically combine with the corresponding products in vitro and in vivo. Antigens have two important characteristics: immunogenicity and immunoreactivity. Immunogenicity refers to the ability of an antigen to induce a specific immune response, producing antibodies or sensitized lymphocytes. Immunoreactivity refers to the ability to specifically bind to the corresponding immune effector (antibody or sensitized lymphocyte) in vitro and in vivo. Generally, antigens can be divided into two categories: infectious antigens and non-infectious antigens. Infectious antigens include components derived from fungi, bacteria and viruses. Non-infectious antigens include components from food, plants, dust, and synthetic and cell surface proteins.
Figure 1. Antigen-antibody complex interaction in immune system.
Veterinary Antigens
As the world's population continues to grow, so does the demand for poultry, livestock, aquaculture and pet breeding. However, the worldwide spread of animal diseases is putting these industries at risk. Infectious animal diseases not only cause economic losses due to animal deaths and reproductive decline, but also affect the safety of meat products. Therefore, the diagnosis of animal diseases is crucial. Animal pathogen testing is an effective method for diagnosis and control of animal diseases and is widely used in animal disease diagnostic laboratories. It has the advantages of high sensitivity, high specificity, high throughput detection and ease to use. Currently, researchers have developed a series of animal pathogens suitable for ELISA, colloidal gold-based lateral flow immunoassay (LFIA), chemiluminescence immunoassay (CLIA), turbidimetric inhibition immunoassay (TINIA), and other immunoassays.
BioVenic is a supplier of biological reagents and kits, and has been developing diagnostic reagents for animal pathogens for many years. Our goal is to be a great company that improves the health and well-being of companion animals and livestock. We have a professional antigen development technology platform and research team who have extensive experience in veterinary diagnostics and kit development, and we offer you a range of relevant antigens for livestock, poultry and companion animals to detect animal diseases caused by coronaviruses, African swine fever virus, Rift Valley fever virus, Toxoplasma gondii and Borrelia. If you have any needs, please feel free to contact us. We will provide you with high-quality products according to your needs.
