Immunoglobulins are animal proteins with antibody activity, consisting of two identical light chains and two identical heavy chains linked by disulfide bonds to form a Y structure. Immunoglobulins are divided into five categories, namely immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), immunoglobulin D (IgD) and immunoglobulin E (IgE). When a pathogen enters the cat's body to cause disease, its immune system will spontaneously attack the invading pathogen to maintain homeostasis. Immunoglobulins are the main spearhead of the immune system's attack on foreign invaders such as pathogens. They block pathogens from attacking cats by specifically binding to antigens to detect or treat related diseases.
Figure 1. Illustration of the different classes of immunoglobulins IgA, IgG, IgD, IgE, IgM (Batra, et al., 2016).
Cat Immunoglobulin Antibodies Applications
Antibodies perform various functions during the immune response, they capture and block invading antigens or induce phagocytic cells to ingest and digest pathogens. In addition, antibodies may also bind to body cells, allowing NK cells to selectively kill cells. Antibodies are commonly used in a variety of methods for diagnosing feline disease, such as immunohistochemistry, ELISA, Western blot, FACS, etc. We need to choose appropriate detection methods and antibodies according to different research purposes.
BioVenic is a supplier of biological reagents and kits, and has been developing diagnostic reagents for animal pathogens for many years. Our goal is to be a great company that improves the health and well-being of pets, humans and livestock. We have a professional team with extensive experience in veterinary diagnostics and reagent development. We can provide you with anti-cat IgG antibodies that specifically recognize cat IgG, which can be used to detect or purify specific targets. Our high-quality products enable you to study immune responses and pathogens in cats. If you have any needs, please feel free to contact us.
Reference
- Batra, Jyoti, and Anurag S. Rathore. "Glycosylation of monoclonal antibody products: Current status and future prospects." Biotechnology Progress 32.5 (2016): 1091-1102.
