Cell differentiation molecules (CD molecules or CD antigens) are cell surface molecules that are closely related to the function of immune cells. Some CD molecules only exist in specific immunocompetent cell groups, such as the most common CD8 and CD4 are markers of T suppressor cells and T helper cells, respectively. CD molecules can be used to study different stages of immune cells such as origin, differentiation and maturation, and they are of great significance in the classification of lymphocytes and the diagnosis of related diseases.
Rabbit Cell Surface and CD Marker Antibodies
Researchers have studied CD antigens primarily in humans and laboratory animals and have varying degrees of knowledge about CD molecules in different animals. Rabbits are commonly used as model animals in biomedical research, but the lack of rabbit CD marker monoclonal antibodies has hindered the study of rabbit immune system function. To this end, researchers have developed a series of rabbit CD marker antibodies for differentiating different rabbit cells, such as T cells, B cells, granulocytes, etc. The following are some of the rabbit CD markers.
| Cell Type | CD Marker | Description |
| T cell/ B cell | CD4 | Rabbit CD4 is a T helper cell-expressed type I transmembrane glycoprotein containing 434 amino acids with an additional N-terminal signal peptide. |
| CD8 | Rabbit CD8 binds to cells bearing MHC class I molecules, which are adhesion molecules for cell-to-cell interactions and is expressed by a subset of T lymphocytes with cytotoxic/suppressive activity. | |
| CD25 | Rabbit CD25 is expressed on activated T lymphocytes and is a 55 kDa cell surface antigen. | |
| CD44 | Rabbit CD4 is a glycoprotein with a molecular size of about 95 kDa, which can be expressed in a variety of cells, including T cells, thymocytes, B cells, granulocytes, and macrophages. | |
| CD45 | CD45 is a type 1 transmembrane molecule and one of the most abundant cell surface glycoproteins. It is only expressed in immature and mature leukocytes, including T and B cells, macrophages, etc. | |
| Granulocytes | CD11b | Rabbit CD11b, also known as integrin α M chain and MAC-1, is a CD11 antigen-like family member that recognizes monocytes, macrophages and neutrophils. |
BioVenic is a company that develops veterinary antibodies to diagnose various animal diseases. Our R&D staff has extensive experience working in the field of molecular biology and immunology. We can provide you with a series of rabbit CD marker antibodies to identify rabbit leukocyte subsets and diagnose related diseases. All of our products have undergone rigorous testing and quality control, and have the advantages of high batch-to-batch consistency, high purity, high specificity, and low background signal. They are suitable for flow cytometry, immunohistochemistry, and immunoprecipitation. If you have any needs, please feel free to contact us.
