To date, four types of antibodies have been identified in rabbits: IgA, IgE, IgG, and IgM. There are 14 IgA subtypes in rabbits and only one IgG subtype. Different types and subtypes of rabbit antibodies have different molecular weights, because the number of interchain disulfide bonds varies, the degree of oligomerization of the immunoglobulin molecules caused by interchain disulfide bonds varies, and the number of immunoglobulin domains in the heavy chain region varies. The common rabbit IgG type has a molecular weight of 150 KD under non-reducing conditions and contains two heavy chains (about 50 KD each) and two light chains (about 25 KD each). Under reducing conditions, the molecular weights of the heavy and light chains are 50 and 25 kD, respectively.
The production of rabbit recombinant protein is to use gene recombination technology to obtain a recombinant vector connected with gene fragments that can be translated into the target protein, and then transfer it into a host cell that can express the target protein to obtain specific rabbit recombinant protein molecules, such as recombinant rabbit IP-10, recombinant rabbit interferon gamma, recombinant rabbit interleukin-2, recombinant rabbit interleukin-13, etc. The production of recombinant proteins in vitro mainly includes four major systems: prokaryotic protein expression, mammalian cell protein expression, yeast protein expression and insect cell protein expression.
BioVenic is a company that develops veterinary antibodies for the diagnosis of a wide range of animal diseases. We have a state-of-the-art antibody development platform, and our R&D staff has extensive experience working in the field of molecular biology and immunology. We obtain anti-rabbit Ig antibodies by introducing immunoglobulin (Ig) from rabbits into the immune system of an available host species (e.g. mouse, goat, donkey, etc.). Our rabbit antibodies include monoclonal and polyclonal antibodies to rabbit cytokines, CD markers and immunoglobulins, and our rabbit recombinant proteins include recombinant rabbit interferon, recombinant rabbit interleukin and recombinant rabbit leukemia inhibitory factor. All of our products have undergone rigorous testing and quality control, and have the advantages of high batch-to-batch consistency, high purity. If you have any needs, please feel free to contact us.