Recombinant Rabbit Interleukin-1 Alpha

Description:

Recombinant rabbit interleukin-1 alpha (IL-1α) is a recombinant protein corresponding to aa 113-267 of native rabbit IL-1α.
Interleukin-1α is a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily. It is secreted by activated macrophages and monocytes and is involved in the modulation of a wide range of immune and inflammatory responses.
IL-1α and the closely related IL-1β, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a.

Product Form:

Purified recombinant protein - lyophilized.

Reconstitution:

Reconstitute with 20 μl sterile PBS containing 0.1% carrier protein.

Preparation:

Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography.

Buffer :

Phosphate buffered saline.

Preservative Stabilisers:

10% Trehalose.

Purity:

>95% by SDS PAGE analysis.

Protein Molecular Weight:

17.8 kDa.

Regulatory:

For research purposes only.

Guarantee:

12 months from date of despatch.

Application:

ELISA, Western blotting.

Storage:

Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted.

Note:

Avoid repeated freezing and thawing as this may denature the protein.