Veterinary Microarrays

Bacteria and viruses are major pathogens causing disease in livestock, poultry and wildlife, and their rapid detection and characterization is important for animal health, food safety, public health and environmental monitoring. In the past decades, researchers have developed several molecular diagnostic methods based on nucleic acid detection techniques for the diagnosis of animal diseases. Microarrays are a method for high throughput qualitative or quantitative determination of biomolecules (e.g., DNA, RNA, proteins, etc.) based on a two-dimensional array on a solid substrate (usually a slide or silicon film). It is widely used in gene expression research, genotyping, sequence analysis and diagnosis due to its advantages of short detection time, higher sensitivity and high-throughput results. The advent of this method is important for rapid diagnosis and control of animal diseases as well as for reducing economic losses.

Figure 1. Composite Likelihood Maximization Method (CLiMax) analysis of microarray results detected Porcine circovirus-2 (PCV-2), torque teno sus viruses (TTSuVs), and porcine endogenous retroviruses (PERVs) in the PCV-2 lymph node–derived inoculum (Jaing, Crystal J., et al., 2015).

Veterinary Microarrays

In veterinary diagnostics, microarrays have been used to study pathogenesis and host-pathogen interactions as well as the detection and typing of various animal pathogens. It is a multiplexing technique in which thousands of DNA oligonucleotides are immobilized in a pre-set arrangement on a centimeter-square chip substrate (substrate or carrier), called probes. These immobilized molecular probes form a high-density DNA microarray on the substrate. Probe specific hybridization is quantified by detection of fluorophores, silver or chemiluminescence to obtain information on the number and sequence of sample molecules for large-scale, high-density studies of gene sequence and function. Currently, researchers have developed a series of microarrays for a variety of different animals, such as rabbit gene expression microarray, bovine gene expression microarray, canine gene expression microarray, pig gene expression microarray, etc.

With the development of veterinary molecular diagnostics, various microarrays have been developed for gene expression and genotyping in cats, dogs, cattle, horses and other animals. BioVenic, a supplier of biological reagents and kits, has been developing reagents for diagnosing animal diseases for many years. Our goal is to be a great company that improves the health and well-being of companion animals and livestock. We have a professional microarray development technology platform and a research team with extensive experience in veterinary diagnostics, gene expression, and molecular diagnostic reagent development, so we can provide you with a variety of veterinary microarrays to obtain biological information on a wide range of animal pathogens. If you have any needs, please feel free to contact us. We will provide you with high-quality products according to your needs.