Human anti Bovine Interleukin-22

Description:

Human anti bovine interleukin-22, clone AbD20463 recognizes bovine interleukin-22 (IL-22).
IL-22 is a T and NK cell cytokine, a member of IL-10 cytokine family and is expressed by mitogen activated bovine peripheral blood γδ T cells. IL-22 is rapidly produced by splenic cells and can be produced by Th17 cells. IL-22 takes part in regulating the immune responses of adaptive and innate immune systems.

Human anti bovine interleukin-22 has been successfully used to analyze IL-22 expression in PBMC from M. bovis. – infected cattle. Bovine tuberculin induced IL-22 and IL-17A production in M. bovis. infected cattle was observed in both CD4+ T cells and γδ T cell populations.

Product Form:

This antibody is supplied as a liquid.

Preparation:

Metal chelate affinity chromatography.

Buffer :

Phosphate buffered saline.

Preservative Stabilisers:

0.01% Thiomersal.

Immunogen:

Fc-fusion protein containing the amino acid sequence 34-190 from bovine interleukin-22.

Approx. Protein Concentrations:

Antibody concentration 0.5 mg/ml.

Regulatory:

For research purposes only.

Guarantee:

12 months from date of despatch.

Application:

ELISA.

Storage:

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Note:

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.