Description:
Mouse anti bovine CD14, clone CAM36A, recognizes bovine CD14. CD14 is a co-receptor for bacterial lipopolysaccharide (LPS) and mediates the innate immune response. It is expressed at high levels on the surface of circulating monocytes, macrophages but also on bovine polymorphonuclear neutrophil leukocytes (PMN). Additionally, in cattle the soluble form of CD14 can be found present in the serum and milk. CD14 signals through TLR4, MyD88, TIRAP and TRAF6 activating NFkB and eliciting the inflammatory response.
Product Form:
Concentrated tissue culture supernatant - liquid.
Preparation:
Concentrated tissue culture supernatant clarified by filtration through a 0.2 micrometer filter.
Buffer :
Serum free tissue culture medium containing proprietary protein free supplement.
Preservative Stabilisers:
0.09% Sodium azide (NaN3).
Immunogen:
Activated goat lymphocytes.
Approx. Protein Concentrations:
IgG concentration 1.0 mg/ml.
Regulatory:
For research purposes only.
Guarantee:
12 months from date of despatch.
Application:
Flow cytometry, functional assays.
Note:
DO NOT FREEZE.
Should this product contain a precipitate we recommend microcentrifugation before use.
Product Type:
Monoclonal antibody
Species Cross-Reactivity:
Goat, sheep, bison, cat, dog