Description:
Mouse anti bovine CD8a, clone 7C2B, recognizes bovine CD8a. CD8a is a coreceptor for MHC I molecules. It is involved in the activation of the cytotoxic T-cell response and the clearance of virally infected cells. CD8 is predominantly present either as homodimer or a multimer of the alpha chain or as heterodimer of the alpha and beta chains. Bovine CD8 differs from the CD8 molecules of other animal species and shares 57.85% identity with swine, 37.70% with mouse, 27.50 % with chicken, and 20.69% identity with carp.
Mouse anti Bovine CD8a, clone 7C2B recognizes bovine CD8 lymphocytes and gamma delta CD8+ lymphocytes. In addition it reacts with the CD8 lymphocytes of water buffalo.
Product Form:
Concentrated tissue culture supernatant - liquid.
Preparation:
Concentrated tissue culture supernatant clarified by filtration through a 0.2 micrometer filter.
Buffer :
Serum free tissue culture medium containing proprietary protein free supplement.
Preservative Stabilisers:
0.09% Sodium azide (NaN3).
Approx. Protein Concentrations:
IgG concentration 1.0 mg/ml.
Regulatory:
For research purposes only.
Guarantee:
12 months from date of despatch.
Application:
Flow cytometry, functional assays.
Note:
DO NOT FREEZE. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Type:
Monoclonal antibody
Species Cross-Reactivity:
Goat, sheep, bison