Description:
Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic α-chain noncovalently bound to the invariant β2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes which are usually cytotoxic T cells. The monoclonal antibody F21-21 also reacts with turkey β2-microglobulin.
Reactivity:
Chicken, Turkey
Immunogen:
Affinity purified chicken MHC-I molecules
Alternative Names:
MHC Class I, B-F
Conjugate:
PE (R-phycoerythrin)
Buffer :
Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Recommended Storage:
2-8°C, Avoid exposure to light, Do not freeze
Application:
Flow cytometry
Immunohistochemistry
Immunoprecipitation
Western blot
Purification
Specificity:
Chicken/Turkey β2-Microglobulin