Mouse Anti-Chicken Bu-1b-PE (5-11G2)

Description:

Chicken Bu-1b, a product of the Bu-1b allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. In chickens heterozygous for the Bu-1 alleles (Bu-1a/b), Bu-1a does not exhibit allelic exclusion. The monoclonal antibody 5-11G2 reacts with lymphoid cells from CHA and H.B14Ab strains but does not react with cells from H.B14Aa

Reactivity:

Chicken

Host:

Mouse

Immunogen:

Bursa cells from two- to five-week-old CHA (Bu-1b) strain chickens.

Alternative Names:

ChB6.2

Conjugate:

PE (R-phycoerythrin)

Buffer :

Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer

Clonality:

Monoclonal

Concentration:

0.1 mg/mL

Recommended Storage:

2-8°C; Avoid exposure to light; Do not freeze

Application:

Flow cytometry
Immunohistochemistry-frozen sections
Immunocytochemistry
Immunoprecipitation
Apoptosis