Mouse Anti-Chicken CD1.1-BIOT (CB3)

Description:

CD1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1 cells and CD8α cells. CD1.2 is expressed in TCRγδ cells but is nearly undetectable in TCRαβ. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.

Reactivity:

Chicken

Host:

Mouse

Immunogen:

Lymphocytes from the bursa of Fabricius of outbred chickens

Conjugate:

BIOT (Biotin)

Buffer :

Phosphate buffered saline containing < 0.1% sodium azide

Clonality:

Monoclonal

Concentration:

0.5 mg/mL

Volume:

1.0 mL

Recommended Storage:

2-8°C

Application:

Flow cytometry
Immunohistochemistry-frozen sections
Immunocytochemistry
Immunoprecipitation