Description:
ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens about 90% of the thymocytes as well as a subpopulation of peripheral lymphocytes, which represent recent thymic emigrants are ChT1 positive. Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. The monoclonal antibody CT1 also recognizes the ChT1 antigen in quail cortical thymocytes.
Reactivity:
Chicken, Quail
Immunogen:
Chicken thymocytes
Alternative Names:
Chicken thymocyte receptor, chicken T cell thymocyte Ag 1
Conjugate:
FITC (Fluorescein)
Buffer :
Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Recommended Storage:
2-8°C, Avoid exposure to light
Application:
Flow cytometry
Immunoprecipitation
Specificity:
Chicken/Quail ChT1