Description:
The monoclonal antibody RDR34 reacts with RLA-DR-transfected cells but not with RLA-DQ-transfected cells. In normal adult rabbits, the antibody reacts with 50-60% of peripheral blood leukocytes and splenocytes. It has also been reported that the antibody stains lymphocytes in the thymic medulla and some cells in the cortex, periportal cells in the liver, and synovial lining cells (e.g., infiltrating macrophages) in inflamed synovium. DRα transcripts have been detected in appendix, bone marrow, spleen, and to a lesser extent in lymph nodes, lung, liver, and other organs.
Immunogen:
Rabbit leukemic B cell line
Alternative Names:
MHC Class II, leukocyte antigen
Conjugate:
PE (R-phycoerythrin)
Buffer :
Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer
Recommended Storage:
2-8°C, Avoid exposure to light, Do not freeze
Application:
Flow cytometry
Immunohistochemistry-frozen sections
Immunohistochemistry-while mount
Immunoprecipitation
Isotype:
Mouse (BALB/c) IgG2bκ
Specificity:
Rabbit RLA-DR