Mouse AT1R IgG Antibody ELISA

Product Overview:

This mouse AT1R IgG antibody ELISA is designed for the determination of mouse antibodies (IgG) against the angiotensin II receptor subtype I in serum and plasma.

Product Description:

Angiotensin II is a peptide hormone which causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It occupies an important role in the Renin-Angiotensin-System (RAS). Angiotensin II mediates the effects through G-Protein-coupled receptors, the Angiotensin receptors. The occurrence of autoantibodies against AT1 receptor is associated with an increased risk of an immunologic rejection after organ transplantation. The presence of AT1 autoantibodies correlate with the existence and course of Scleroderma.
This Mouse Anti Angiotensin Receptor 1 (ATR1) IgG Antibody ELISA Assay Kit is designed for the determination of mouse antibodies (IgG) against the Angiotensin II receptor subtype I in serum and plasma.

Sensitivity:

1.25 U/ml

Dynamic Range:

1.25 – 40 U/ml

Incubation Time:

3.5 hours

Sample Type:

Plasma, serum

Sample Size:

100 µl

Specimen Collection and Handling:

Dilute the samples with diluent using 1:100 dilution (eg. 5 µl serum or plasma + 495 µl diluent). If samples generate values outside the standard curve, the dilution factor may be quite varied. Store the undiluted samples at room temperature for 48 hours, 2-8°C 4- days, and long-term storage for up to 12 months at –20 °C. Avoid repeated freeze-thaw cycles.