Rabbit anti Chicken Interleukin-1 Beta:Preservative Free

Description:

Rabbit anti chicken interleukin-1 beta antibody recognizes chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta.

IL-1 is a major regulator in both innate and adaptive immune responses, plays an important role in the regulation of acute inflammation and has also been implicated in many other processes, including both fever and fibrinogen induction. The previous names by which IL-1 has been known includes lymphocyte activating factor, endogenous pyrogen, catabolin, hemopoietin-1, melanoma growth inhibition factor, and osteoclast activating factor, reflecting its widespread cell expression.

Chicken models indicate physiological similarities between chIL-1beta and mammalian IL-1beta in relation to its neural distribution and several factors have been shown to induce chIL-1beta secretion, including protein kinase C (PKC), Calmodulin-dependent protein kinase, lipopolysaccharide, phorbol esters, calcium and silica.

Rabbit anti chicken interleukin-1 beta antibody neutralizes chicken IL-1 beta.

Product Form:

Purified IgG - liquid.

Preparation:

Antisera to chicken Interleukin-1β were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography on protein G.

Buffer :

Phosphate buffered saline.

Preservative Stabilisers:

None present.

Immunogen:

Recombinant chicken IL-1β.

Approx. Protein Concentrations:

IgG concentration 0.5 mg/ml.

Regulatory:

For research purposes only.

Guarantee:

12 months from date of despatch.

Application:

ELISA, functional assays, western blotting.

Storage:

Store at -20°C only.

Note:

Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.