Rabbit anti Sheep TNF Alpha

Description:

Rabbit anti sheep TNF alpha recognizes sheep tumor necrosis factor (TNF) alpha, a 25.5 kDa regulatory cytokine.

TNF alpha is produced by activated macrophages, monocytes, endothelial cells, fibroblast and both T and B lymphocytes. Production of ovine TNF alpha can be induced by a variety of factors, dependant upon cell type, and includes bacterial toxins, IL-1, PDGF, IFN beta, NGF, oncostatin M and viral infections. TNF alpha functions in the regulation of immune cells, is able to induce fever, apoptotic cell death, sepsis, cacheria, inflammation and to inhibit tumorigenesis and viral replication.

Product Form:

Purified IgG - liquid.

Preparation:

Antiserum to sheep TNF alpha was raised by repeated immunization of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Buffer :

Phosphate buffered saline.

Preservative Stabilisers:

0.09% Sodium azide (NaN₃).

Immunogen:

Recombinant ovine TNF alpha.

Approx. Protein Concentrations:

IgG concentration 1.0 mg/ml.

Regulatory:

For research purposes only.

Guarantee:

12 months from date of despatch.

Application:

ELISA, western blotting.

Storage:

Store at +4°C.

Note:

DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.