Overview

Description:

Rat anti dog CD90, clone YKIX337.217 recognizes the canine Thy-1 cell surface antigen, also known as CD90. CD90 is a 20-30 kDa glycoprotein expressed by peripheral T lymphocytes, monocytes, thymocytes and vascular endothelium in dogs.
Rat anti dog CD90, clone YKIX337.217 has been demonstrated to deplete T cells when administered in vivo, and to block Con A driven T cell proliferation in vitro.
Rat anti dog CD90, clone YKIX337.217 is a useful clone for the immunophenotyping of cells and discrimination between a wide variety of lymphoproliferative disorders in dogs.

Product Form:

Purified IgG - liquid.

Preparation:

Purified IgG prepared by affinity chromatography on protein A from tissue culture supernatant.

Buffer :

Phosphate buffered saline.

Preservative Stabilisers:

0.09% Sodium azide.

Carrier Free:

Yes.

Immunogen:

Con A stimulated canine T cells.

Approx. Protein Concentrations:

IgG concentration 1.0 mg/ml.

Fusion Partners:

Spleen cells from immunised DA rats were fused with cells of the rat Y3/Ag1.2.3 myeloma cell line.

Regulatory:

For research purposes only.

Guarantee:

12 months from date of despatch.

Application:

Flow cytometry, immunoprecipitation.

Storage:

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Note:

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

Product Type:

Monoclonal antibody

Clone:

YKIX337.217

Isotype:

IgG2b

Specificity:

CD90

Target:

Dog

Rat anti Dog CD90

Overview

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