Recombinant Dog Interleukin-1 beta

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Recombinant Dog Interleukin-1 beta
Products Name
Recombinant Dog Interleukin-1 beta
Cat.No.
CC0007
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Overview

Description:
Recombinant dog interleukin-1 beta (IL-1β) is a recombinant protein corresponding to a 152 amino acid sequence of native canine IL-1β.

Interleukin-1β is a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily. It is secreted by activated macrophages and monocytes and is involved in the modulation of a range of immune and inflammatory responses.

IL-1β and the closely related IL-1α, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a.
Product Type:
Recombinant Protein
Specificity:
IL-1 Beta
Target:
Dog
Product Form:
Purified recombinant protein - lyophilized.
Reconstitution:
Reconstitute with 20 μl sterile PBS containing 0.1% carrier protein.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. BioVenic recommend that the vial is gently mixed after reconstitution.
Preparation:
Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography.
Buffer :
Phosphate buffered saline.
Preservative Stabilisers:
10% Trehalose.
Purity:
> 95% by SDS PAGE analysis.
Protein Molecular Weight:
17.5 kDa.
Regulatory:
For research purposes only.
Guarantee:
12 months from date of despatch.
Application:
ELISA, western blotting.
Storage:
Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.

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