Rodent Urocortin 1 ELISA Assay

Product Overview:

This rodent urocortin 1 ELISA assay is used for quantitative determination of urocortin 1 in mouse/rat plasma and serum samples. The kit is characterized by its sensitive quantification and high specificity. In addition, it has no influence by other components in samples. Mouse/rat urocortin 1 standard is highly purified synthetic product.

Product Description:

Urocortin (Urocortin1: Ucn1) is first identified in rat, and later in human and mouse3. It is the second mammalian member of the CRF family. Rat and mouse Ucn1 have the same amino acid sequence and display 95% structure homology to human Ucn1, 45% to CRF and 63% to urotensin.

In the rat, Ucn1 immunoreactivity (IR) was shown to distribute widely in central nervous system, endocrine organs, and digestive system and its concentration was highest in pituitary (11 pmol/g, w.w.). Koziez, Yanaihara et al. used a polyclonal antibody against rat Ucn1 to define the distribution of Ucn1-IR in rat central nervous system and found a large number of neurons with Ucn1-IR in rat brain.

Dynamic Range:

1.53 – 100 ng/ml

Incubation Time:

21 hours

Sample Type:

Mouse/rat serum, plasma

Sample Size:

10 µl